How Chronic Stress is Rotting Our Brain


…and how Randy’s Remedy can help

Chronic stress can have serious and lasting negative effects on physical and mental health. It impairs normal cognitive function and can cause anxiety, depression, headaches, sleep problems, and weight gain. Left unchecked, people suffering from chronic stress can develop heart disease and digestive problems. Randy’s Remedy contains natural cannabinoids from hemp and may be useful in combating the negative effects of chronic stress.

Natural Cannabinoids in Hemp Improves Memory and Cognition.

Randy’s Remedy products are made from hemp. The natural cannabinoids found in hemp have been found to improve cognitive function and memory by improving symptoms related to anxiety and depression. When an individual is stressed or anxious, blood flows from the frontal lobe region of the brain as part of the fight of flight response. Bacopa monnieri, a nootropic herb that has been used in traditional medicine for longevity and cognitive enhancement, is said to improve cognition by reducing anxiety in the person. Results indicate that this is because a person is more able to think clearly when they are relaxed. When a person is stressed out, blood flows away from the frontal lobe of the brain as a symptom of fight or flight.

The frontal lobe region of our brain is where decisions are made. It is the region responsible for our “executive functions.” This includes attentional control, inhibitory control, working memory, and cognitive flexibility. It is also where reasoning, problem solving, and planning occur. All of these activities are essential for the conscious control of behaviors. Monitoring those behaviors is necessary to facilitate the successful attainment of chosen goals. In other words, the frontal lobe is where we think about what we want, plan how to get it, and then execute that plan successfully.

So how does the frontal lobe relate to Randy’s Remedy? Well, I have mentioned how stress and anxiety can reduce blood flow to the frontal lobe of the brain. Reducing blood flow is an invitation for rash decision making; there is less room for forethought, deliberation, and careful planning. However, by using Randy’s Remedy to reduce the fight or flight stress response, proper blood flow to the brain is preserved which in turn allows for better decision making.

Chronic Stress is Bad Your Health

The ingredients of Randy’s Remedy may reduce stress and alleviate the negative effects of chronic stress. Chronic stress is more common than you might think. It has become more common in industrialized societies that seem to run on stress, hunger, caffeine, and adrenaline. Long hours at work combined with long commutes in traffic make it very difficult to escape the stress of modern life that has become part of our everyday lives.

A little stress may not bad, but chronic stress can be terrible for your overall health and wellbeing. Specifically, chronic stress inhibits the ability of your immune system to fight off infections. This increases the likelihood of becoming sick as well as the risk of weight gain and Type 2 Diabetes. Chronic stress has also been linked to peptic ulcers and other diseases of the gut as well as causing a buildup of plaque in the arteries. Chronic stress is also strongly correlated with various psychiatric conditions which may be linked to its effects on the immune system.

Acute Stress is not the same as Chronic Stress

It’s important to remember that the amount of stress is less important than the frequency. Acute stress triggers a lasting increase in the transmission of glutamate. Glutamate is a neurotransmitter which sends signals from one neuron to the next. In response to acute stress the pace at which signals are sent across the prefrontal cortex of the brain increases for a period of time after the situation has been resolved, but not during the acute stress.

At this point it is important to note that acute stress is positively correlated with what is called associative memories, those memories which are closely tied to a particular context. This phenomenon is also called associative learning, whereby acute stress is used to reinforce a learned response to a stimulus. For example, military training often involves performing tasks under extreme stress. The tasks themselves are typically introduced under normal conditions and then tested and reinforced under stressful conditions. The results are behaviors which become second nature; behaviors that are able to be performed without conscious consideration.

Chronic stress causes elevated levels of corticosterone to be released which impairs long-term potentiation (LTP). LTP is a long-lasting strengthening of synapses between nerve cells. Impairment of LTP may cause long term depression in the hippocampus. I have found that regular use of Randy’s Remedy has helped me to reduce my stress and mitigates the negative effects of chronic stress. Many of our customers report feeling much more relaxed and less stressed when confronted by stressful situations. In addition they also report that Randy’s Remedy products are helping them to think more clearly and make calmer, more rational decisions. One customer even reported that she had been able to kick a 20 year addiction to diet soda. She said she just didn’t feel like drinking it anymore.

This makes sense given all that we know about the benefits of the natural cannabinoids from hemp which are found in Randy’s Remedy products.

How Chronic Stress…..

affects memory: Compared to acute stress, chronic stress takes a heavy toll on the brain and acts like a slow poison degrading and depressing executive functions while also impairing our ability to recognize objects and utilize our working memory. Over time, chronic stress increases your susceptibility to mental illness and reduces the number of connections in our brain.

affects anxiety: Chronic stress reduces blood flow to the part of the brain responsible for higher functioning and reasoned thought. On the other hand, it preserves blood flow to the amygdala which is the part of the brain responsible for fear conditioning and anxiety like behavior. This means that chronic stress reinforces fear and anxiety causing you to subconsciously behave and act in ways that are driven by fear and anxiety, not thoughtful consideration. These negative stress responses are not without their utility, fear and anxiety both motivate action in a fight or flight situation where the consequences may be life or death.

affects glutamate transmission: Chronic stress suppresses the transmission of glutamate in the prefrontal cortex (PFC) of young male rats. The PFC, it seems, is particularly sensitive to chronic stress, particularly during the adolescent period when this region is still developing. By suppressing Glutamatergic transmission in the prefrontal cortex, chronic stress prevents it from functioning properly, hindering executive functioning. When this happens while the PFC is still developing the result can be profound and may even be permanent.

Randy’s Remedy are helpful here because they contain naturally occurring cannabinoids found in hemp which help counter some of the negative effects of chronic stress. This leads to improvements in health and overall wellbeing.

Check them out at and enjoy life to the last drop!